“To understand what it means to live longer, you have to understand what ends life.”
— Dr. Peter Attia
Peter Attia, MD (@PeterAttiaMD), is the founding father of Early Medical, a medical follow that applies the rules of Medicine 3.0 to sufferers with the objective of lengthening their lifespan and concurrently enhancing their healthspan. He is the host of The Drive, probably the most fashionable podcasts overlaying the matters of well being and drugs.
Dr. Attia acquired his medical diploma from the Stanford University School of Medicine and skilled for 5 years on the Johns Hopkins Hospital generally surgical procedure, the place he was the recipient of a number of prestigious awards, together with Resident of the Year. He spent two years on the National Institutes of Health as a surgical oncology fellow on the National Cancer Institute, the place his analysis centered on immune-based therapies for melanoma.
His new guide is Outlive: The Science and Art of Longevity (3/28).
Please get pleasure from!
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#661: Dr. Peter Attia — The Science and Art of Longevity
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Want to listen to Peter’s final time on the present? Listen to this dialog by which we focus on liquid biopsies, the 4 pillars of train somebody in search of to enhance their metabolic well being ought to perceive, strategies for remedying fashionable posture issues, elevating youngsters to be habitually energetic adults, the three levers of Peter’s dietary framework, growing scientific literacy, present pharmacological candidates for extending lifespan and healthspan, the whole lot you ever wished to find out about zone two coaching, and way more.
#517: Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and the three Most Important Levers to Pull
What was your favourite quote or lesson from this episode? Please let me know within the feedback.
SCROLL BELOW FOR LINKS AND SHOW NOTES…
SELECTED LINKS FROM THE EPISODE
- Connect with Dr. Peter Attia:
Website | Twitter | Facebook | Instagram | YouTube
- Outlive: The Science and Art of Longevity by Peter Attia | Amazon
- Engineer Your Own Personalized Longevity Playbook | Early Medical
- The Peter Attia Drive Podcast
- Dr. Peter Attia on Longevity Drugs, Alzheimer’s Disease, and the three Most Important Levers to Pull | The Tim Ferriss Show #517
- Peter Attia, M.D. — Fasting, Metformin, Athletic Performance, and More | The Tim Ferriss Show #398
- Dr. Peter Attia vs. Tim Ferriss | The Tim Ferriss Show #352
- Dr. Peter Attia on Life-Extension, Drinking Jet Fuel, Ultra-Endurance, Human Foie Gras, and More | The Tim Ferriss Show #50
- DEXA Scan (DXA): Bone Density Test, What Is It and How It’s Done | Cleveland Clinic
- Assessment of Lean Mass and Physical Performance in Sarcopenia | Journal of Clinical Densitometry
- Fat-Free Mass Index (FFMI) Calculator | Omni Calculator
- AMA #11: All Things Fasting | The Peter Attia Drive #89
- How Much Protein Should You Eat? | Peter Attia
- Food Sources for Nine Essential Amino Acids | Food Unfolded
- The Smart Diet Coaching App | Carbon
- 5 Proven Benefits of Branched-Chain Amino Acids (BCAAs) | Healthline
- mTOR (Mechanistic Target of Rapamycin) | Wikipedia
- Lacto-Ovo-Vegetarian Diet: Benefits, Downsides, and Meal Plan | Healthline
- What is Ketosis? The Science Explained. | Peter Attia
- Jocko Willink, Retired Navy SEAL: Objective, Strategy, and Tactics, Leadership, Protocols, Dealing With Death, and Applying the Many Lessons Learned from War | The Peter Attia Drive #55
- USA Causes of Death by Age and Gender | World Life Expectancy
- AMA #41: Medicine 3.0, Developments within the Field of Aging, Healthy Habits in Times of Stress, and More | The Peter Attia Drive #231
- The 4-Hour Body: An Uncommon Guide to Rapid Fat Loss, Incredible Sex, and Becoming Superhuman by Timothy Ferriss | Amazon
- Staying Safe from COVID-19 | Johns Hopkins Medicine
- What If Moore’s Law Applied to Humans as Well? | The Washington Post
- Medicine 1.0, 2.0, and three.0 | Peter Attia, Twitter
- Funny Medicine: Hippocrates and the Four Humours | Gavi
- Scientific Method | Stanford Encyclopedia of Philosophy
- Richard Feynman Teaches You the Scientific Method | Farnam Street
- Dirty Doctors Finished What an Assassin’s Bullet Started: Disregarding New Scientific Information Can Be Deadly | Scientific American
- Treatments for HIV/AIDS | Stanford Health Care
- Treating Hepatitis C | American Liver Foundation
- Nixon’s War on Cancer: Why It Mattered | Fred Hutch Cancer Center
- Neurodegenerative Diseases | NIEHS
- What is ALS (Amyotrophic Lateral Sclerosis)? | The ALS Association
- Huntington’s Disease | National Institute of Neurological Disorders and Stroke
- Is Diabetes Becoming the Biggest Epidemic of the twenty first Century? | International Journal of Health Sciences
- Study Design 101: Randomized Controlled Trial | The Himmelfarb Health Sciences Library
- Reading Mendelian Randomisation Studies: A Guide, Glossary, and Checklist for Clinicians | BMJ
- What Is ApoB? | Pritkin Longevity Center
- Weekly Emails Archives | Peter Attia
- Studying the Studies Archives | Peter Attia
- Study Design 101: Cohort Study | The Himmelfarb Health Sciences Library
- Observational Studies: Epidemiology | Research Guides at Pennsylvania College of Technology
- Research Explained in Practical Summaries (REPS) | Biolayne
- The Man Who Tries Methods, Ignoring Principles, Is Sure to Have Trouble | Quote Investigator
- How to Learn Any Language in Three Months | Tim Ferriss
- AMA #30: How to Read and Understand Scientific Studies | The Peter Attia Drive #188
- Bad Science: Quacks, Hacks, and Big Pharma Flacks by Ben Goldacre | Amazon
- Hills Criteria of Causation
- Bradford Hill Criteria | Wikipedia
- You’re Blowing Smoke up My Ass, Right? | The Bookwormery
- How to Lie with Statistics by Darrell Huff | Amazon
- Dr. Matthew Walker, All Things Sleep — How to Improve Sleep, How Sleep Ties Into Alzheimer’s Disease and Weight Gain, and How Medications (Ambien, Trazodone, and so on.), Caffeine, THC/CBD, Psychedelics, Exercise, Smart Drugs, Fasting, and More Affect Sleep | The Tim Ferriss Show #650
- That Sleep Tracker Could Make Your Insomnia Worse | The New York Times
- Alcohol Archives | Peter Attia
- Sleep & Alcohol: Part 1 | The Matt Walker Podcast
- Sleep & Alcohol: Part 2 | The Matt Walker Podcast
- Nutter Butter Peanut Butter Sandwich Cookies | Amazon
- How to Use a Continuous Glucose Monitor (CGM) to Optimize Your Nutrition (Clip) | The Tim Ferriss Show
- Dexcom Continuous Glucose Monitoring | Dexcom
- FreeModel Libre 2 Continuous Glucose Monitor | Abbott US
- Dietary Carbohydrate Restriction in Type 2 Diabetes Mellitus and Metabolic Syndrome: Time for a Critical Appraisal | Nutrition & Metabolism
- All About Your A1C | CDC
- Raisinets | Amazon
- Exercise Can Raise Blood Glucose (Blood Sugar) | ADA
- Hostel 2 | Prime Video
- Wall Street | Prime Video
- Hawthorne Effect: How It Works and Is It Real? | Investopedia
- VO2 Max: How to Measure and Improve It | Cleveland Clinic
- Muscle Fiber Type Transitions with Exercise Training | NCBI
- Strength Training Can Help Protect the Brain from Degeneration | The University of Sydney
- Concentric, Isometric, and Eccentric Training | Athletic Lab
- Best Hamstring Exercise: Nordic Hamstring Curl to Reduce Risk of Injury | Muscle and Motion
- How to Do a Hip Hinge | Verywell Fit
- Tip: Axial Loading – What You Need to Know | T-Nation
- Top Five Hand Strengthening Exercises For Stronger Hands | Virtual Hand Care
- What is Rucking? | GORUCK
- Training Zones Explained | ACTIVE
- Blood Lactate Measurements and Analysis throughout Exercise: A Guide for Clinicians | Journal of Diabetes Science and Technology
- The Beginner’s Gear Guide for Ski Touring or Skinning | Insider
- The Rucking Company | GORUCK
- Weighted Vest Vs. Rucking | Weight Loss Made Practical
- The Comfort Crisis: Embrace Discomfort to Reclaim Your Wild, Happy, Healthy Self by Michael Easter | Amazon
- Cognitive Health and Neurodegenerative Disease Prevention | Peter Attia
- Physical Exercise and Dementia | Alzheimer’s Society
- Brain-Derived Neurotrophic Factor: A Key Molecule for Memory within the Healthy and the Pathological Brain | Frontiers In Cellular Neuroscience
- A New Frontier for Early Cancer Detection? Discussing the Grail Blood Test. | Peter Attia
- Whole Body MRI Scans | Prenuvo
- Alzheimer’s Genes: Are You at Risk? | Mayo Clinic
- Cystatin C | National Kidney Foundation
- Creatinine | National Kidney Foundation
- FOLFOX Regimen | NCI Dictionary of Cancer Terms
- Breast Cancer Hormone Receptor Status | Estrogen Receptor
- Guy Winch, Ph.D.: Emotional First Aid and How To Treat Psychological Injuries | The Peter Attia Drive #146
- Stuart Smalley’s Daily Affirmation | SNL
- Theranos: A Fallen Unicorn | Investopedia
SHOW NOTES
- [07:00] How and why Peter’s muscle mass has elevated considerably.
- [18:48] Why the lengthy anticipate Outlive: The Science and Art of Longevity?
- [23:19] Objective, technique, and ways.
- [28:50] From Medicine 1.0 to Medicine 3.0.
- [39:04] Randomized management trial outcomes: pointers, not gospel.
- [43:21] Revisiting why and the way one ought to improve their medical literacy.
- [52:44] Avoiding scientific methodology misconceptions.
- [55:43] Austin Bradford Hill.
- [56:22] Observational examine versus randomized management trial.
- [1:00:09] Are sleep trackers downgrading the standard of our sleep?
- [1:02:53] Under what situations does Peter really feel alcohol may be price its downsides?
- [1:06:47] Continuous glucose screens (CGMs).
- [1:18:24] Underutilized metrics and instruments for increasing well being and lifespan.
- [1:25:01] Strength.
- [1:33:11] Rucking round and discovering out about VO2 max.
- [1:38:32] Finding the zone two candy spot.
- [1:41:10] How skinning and rucking have upped my endurance.
- [1:42:24] Rucking vs. weighted vests.
- [1:46:39] Are neurodegenerative illnesses preventable?
- [1:51:47] Helping your physician perceive and embrace Medicine 3.0.
- [1:53:47] How a lot is an oz. of prevention price to you?
- [1:58:23] Early most cancers screening.
- [2:06:33] Outlive chapters.
- [2:08:46] The chapter on emotional well being that nearly didn’t make the guide.
- [2:10:16] Peter’s 47 affirmations.
- [2:14:18] Parting ideas.
MORE PETER ATTIA QUOTES FROM THE INTERVIEW
“Despite what a lot of the epidemiology will tell people, alcohol is not good for you in any dose. It doesn’t mean we shouldn’t drink it at all, but let’s not delude ourselves into thinking it’s actually healthy at some low dose. It’s not.”
— Dr. Peter Attia
“My response to alcohol is, if I drink something that doesn’t taste incredible, I pour it out. I’m never going to tolerate a bad glass of wine, ever. It’s just not worth it.”
— Dr. Peter Attia
“Seven drinks in one day is very different than one drink a day for seven days. It’s the frequency and dose that defines the poison.”
— Dr. Peter Attia
“Not one to just clear the bar, I want to be considerably above the bar.”
— Dr. Peter Attia
“To understand what it means to live longer, you have to understand what ends life.”
— Dr. Peter Attia
“When I went to medical school, I didn’t learn a single thing about nutrition or exercise or sleep or stress management or emotional health. I learned a lot about pharmacology. And it’s tempting at this point to say, ‘Well, pharmacology is either good or bad.’ No, it’s both, right? Pharmacology is good and it’s really valuable, but over-indexing it is bad.”
— Dr. Peter Attia
“Sometimes more data is not always the answer.”
— Dr. Peter Attia
“Any measurement in isolation can be ridiculous and can be gamed. We shouldn’t ignore blood glucose any more than we should ignore body weight or body fat or body composition. We just have to understand that it’s one of many tools that we can look at.”
— Dr. Peter Attia
“To get into that top 2.5 percent of the population where you really start to see an enormous gap between you and everybody else in terms of lifespan, yeah, maybe only a quarter of the population has the potential to get there. But the point is everybody has the potential to be more fit than they are, outside of people who are already doing everything they can. So just going from being in the bottom 25 percent of the population to the 25th to 50th percentile of the population cuts your risk of all-cause mortality in half at any point in time. There’s nothing that compares to that.”
— Dr. Peter Attia
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